| # | Rider | Team | Time | Gap |
|---|---|---|---|---|
| 1 | Daniele Bennati | Lampre-Fondital | 04:11:45 | |
| 2 | Gregory Rast | Phonak Hearing Systems | + 00 | |
| 3 | Gene Bates | Team LPR | + 00 | |
| 4 | Manuele Mori | Saunier Duval - Prodir | + 00 | |
| 5 | Vicente Reynès | Caisse d'Epargne - Illes Balears | + 00 | |
| 6 | Björn Leukemans | Davitamon - Lotto | + 00 | |
| 7 | Błażej Janiaczyk | Team 3C Casalinghi Jet | + 00 | |
| 8 | Cristian Moreni | Cofidis | + 00 | |
| 9 | Paride Grillo | Ceramica Panaria - Navigare | + 00 | |
| 10 | Asle Arvesen Kurt | Team CSC | + 00 | |
| 11 | Eric Baumann | T-Mobile Team | + 01 | + 01 |
| 12 | Daniele Callegarin | Team 3C Casalinghi Jet | + 01 | + 01 |
| 13 | Mikhaylo Khalilov | Team LPR | + 02 | + 02 |
| 14 | Marlon Perez | Team Tenax Salmilano | + 02 | + 02 |
| 15 | Mikel Astarloza | AG2R Prévoyance | + 03 | + 03 |
| 16 | Preben van Hecke | Davitamon - Lotto | + 03 | + 03 |
| 17 | Marco Osella | Team 3C Casalinghi Jet | + 03 | + 03 |
| 18 | Alexandre Bazhenov | Naturino - Sapore di Mare | + 03 | + 03 |
| 19 | Pasquale Muto | Miche | + 03 | + 03 |
| 20 | David Mcpartland | Team Tenax Salmilano | + 04 | + 04 |
| 21 | Vladimir Efimkin | Caisse d'Epargne - Illes Balears | + 05 | + 05 |
| 22 | Paolo Bailetti | Team 3C Casalinghi Jet | + 05 | + 05 |
| 23 | Philippe Schnyder | Selle Italia - Serramenti | + 05 | + 05 |
| 24 | Michael Schär | Phonak Hearing Systems | + 05 | + 05 |
| 25 | Thomas Ziegler | T-Mobile Team | + 06 | + 06 |
| 26 | Leonardo Giordani | Naturino - Sapore di Mare | + 06 | + 06 |
| 27 | David Canada | Saunier Duval - Prodir | + 06 | + 06 |
| 28 | Matej Jurco | Team Milram | + 06 | + 06 |
| 29 | Iván Gutiérrez | Caisse d'Epargne - Illes Balears | + 06 | + 06 |
| 30 | Lorenzo Bernucci | T-Mobile Team | + 07 | + 07 |
| 31 | Lars Bak | Team CSC | + 07 | + 07 |
| 32 | Christophe Riblon | AG2R Prévoyance | + 07 | + 07 |
| 33 | Nicki Sørensen | Team CSC | + 07 | + 07 |
| 34 | Alexander Efimkin | Barloworld | + 07 | + 07 |
| 35 | Alessandro Bertuola | Team Tenax Salmilano | + 07 | + 07 |
| 36 | Bingen Fernández Bustinza | Cofidis | + 07 | + 07 |
| 37 | Niklas Axelsson | Selle Italia - Serramenti | + 07 | + 07 |
| 38 | Steve Morabito | Phonak Hearing Systems | + 08 | + 08 |
| 39 | Mikel Pradera | Caisse d'Epargne - Illes Balears | + 08 | + 08 |
| 40 | Alexander Arekeev | Acqua e Sapone - Caffe Mokambo | + 08 | + 08 |
| 41 | Andrea Tonti | Acqua e Sapone - Caffe Mokambo | + 08 | + 08 |
| 42 | Konstantin Klyuev | Team 3C Casalinghi Jet | + 08 | + 08 |
| 43 | Marco Pinotti | Saunier Duval - Prodir | + 08 | + 08 |
| 44 | Sergio Barbero | Selle Italia - Serramenti | + 09 | + 09 |
| 45 | Inigo Chaurreau | AG2R Prévoyance | + 09 | + 09 |
| 46 | Emanuele Sella | Ceramica Panaria - Navigare | + 09 | + 09 |
| 47 | Roman Kreuziger | Liquigas | + 09 | + 09 |
| 48 | Martin Elmiger | Phonak Hearing Systems | + 09 | + 09 |
| 49 | Daniele de Paoli | Team LPR | + 09 | + 09 |
| 50 | Stéphane Goubert | AG2R Prévoyance | + 10 | + 10 |
| 51 | Oleksandr Kvachuk | Team 3C Casalinghi Jet | + 10 | + 10 |
| 52 | Wim van Huffel | Davitamon - Lotto | + 10 | + 10 |
| 53 | Chris Horner | Davitamon - Lotto | + 10 | + 10 |
| 54 | Pablo Lastras | Caisse d'Epargne - Illes Balears | + 11 | + 11 |
| 55 | Javier Mejias | Saunier Duval - Prodir | + 11 | + 11 |
| 56 | Guido Trentin | Saunier Duval - Prodir | + 11 | + 11 |
| 57 | Volodymir Gustov | Team CSC | + 11 | + 11 |
| 58 | Patrick Mccarty Jonathan | Phonak Hearing Systems | + 11 | + 11 |
| 59 | Oliver Zaugg | Saunier Duval - Prodir | + 12 | + 12 |
| 60 | Luca Solari | Team 3C Casalinghi Jet | + 12 | + 12 |
| 61 | Hugo Sabido | Barloworld | + 12 | + 12 |
| 62 | Przemyslaw Niemiec | Miche | + 12 | + 12 |
| 63 | Daniele Pietropolli | Team Tenax Salmilano | + 12 | + 12 |
| 64 | Valerio Agnoli | Naturino - Sapore di Mare | + 12 | + 12 |
| 65 | John Gadret | AG2R Prévoyance | + 12 | + 12 |
| 66 | Maxime Monfort | Cofidis | + 13 | + 13 |
| 67 | Íñigo Cuesta | Team CSC | + 13 | + 13 |
| 68 | Franco Pellizotti | Liquigas | + 13 | + 13 |
| 69 | Claudio Corioni | Lampre-Fondital | + 13 | + 13 |
| 70 | Maurizio Varini | Ceramica Flaminia | + 13 | + 13 |
| 71 | Leonardo Bertagnolli | Cofidis | + 14 | + 14 |
| 72 | Daniele Nardello | T-Mobile Team | + 14 | + 14 |
| 73 | Rubens Bertogliati | Saunier Duval - Prodir | + 14 | + 14 |
| 74 | Eddy Ratti | Naturino - Sapore di Mare | + 15 | + 15 |
| 75 | Alejandro Valverde | Caisse d'Epargne - Illes Balears | + 20 | + 20 |
| 76 | Philip Deignan | AG2R Prévoyance | + 20 | + 20 |
| 77 | Joaquim Rodríguez | Caisse d'Epargne - Illes Balears | + 20 | + 20 |
| 78 | Julio Perez Cuapio | Ceramica Panaria - Navigare | + 20 | + 20 |
| 79 | Matteo Carrara | Lampre-Fondital | + 21 | + 21 |
| 80 | Andrea Noè | Liquigas | + 21 | + 21 |
| 81 | Amaël Moinard | Cofidis | + 22 | + 22 |
| 82 | Mauro Santambrogio | Lampre-Fondital | + 24 | + 24 |
| 83 | Sylwester Szmyd | Lampre-Fondital | + 24 | + 24 |
| 84 | Santo Anzà | Selle Italia - Serramenti | + 24 | + 24 |
| 85 | Michael Rogers | T-Mobile Team | + 25 | + 25 |
| 86 | Ruggero Marzoli | Lampre-Fondital | + 25 | + 25 |
| 87 | Félix Cárdenas | Barloworld | + 25 | + 25 |
| 88 | Raffaele Ferrara | Team 3C Casalinghi Jet | + 26 | + 26 |
| 89 | Lars Michaelsen | Team CSC | + 04:38 | + 04:38 |
| 90 | Mirco Lorenzetto | Team Milram | + 04:40 | + 04:40 |
| 91 | Tomasz Marczynski | Ceramica Flaminia | + 04:40 | + 04:40 |
| 92 | Fabio Sacchi | Team Milram | + 04:42 | + 04:42 |
| 93 | Danilo Napolitano | Lampre-Fondital | + 04:42 | + 04:42 |
| 94 | Gabriele Bosisio | Team Tenax Salmilano | + 04:42 | + 04:42 |
| 95 | Domenico Pozzovivo | Ceramica Panaria - Navigare | + 04:43 | + 04:43 |
| 96 | Julien Loubet | AG2R Prévoyance | + 04:53 | + 04:53 |
| 97 | Olivier Kaisen | Davitamon - Lotto | + 06:29 | + 06:29 |
| 98 | Hubert Krys | Ceramica Flaminia | + 06:29 | + 06:29 |
| 99 | Alessandro Cortinovis | Team Milram | + 06:29 | + 06:29 |
| 100 | Denis Shkarpeta | + 06:30 | + 06:30 | |
| 101 | Damien Monier | Cofidis | + 06:32 | + 06:32 |
| 102 | Manuele Spadi | Ceramica Flaminia | + 06:32 | + 06:32 |
| 103 | Diego Caccia | Barloworld | + 06:32 | + 06:32 |
| 104 | Alessandro Vanotti | Team Milram | + 06:33 | + 06:33 |
| 105 | Ruslan Pidgornyy | Team Tenax Salmilano | + 06:33 | + 06:33 |
| 106 | Kim Kirchen | T-Mobile Team | + 06:34 | + 06:34 |
| 107 | Giairo Ermeti | Team LPR | + 06:35 | + 06:35 |
| 108 | Stefano Cavallari | Acqua e Sapone - Caffe Mokambo | + 08:29 | + 08:29 |
| 109 | Roberto Traficante | Team LPR | + 09:06 | + 09:06 |
| 110 | Pieter Mertens | Davitamon - Lotto | + 09:06 | + 09:06 |