| # | Rider | Team | Time | Gap |
|---|---|---|---|---|
| 1 | Danilo Di Luca | Liquigas | 04:32:40 | |
| 2 | Mauricio Soler | Barloworld | + 00 | |
| 3 | Kim Kirchen | T-Mobile Team | + 09 | + 09 |
| 4 | Stuart O'grady | Team CSC | + 09 | + 09 |
| 5 | Mikhaylo Khalilov | Ceramica Flaminia | + 09 | + 09 |
| 6 | Cristian Moreni | Cofidis | + 09 | + 09 |
| 7 | Daniele Pietropolli | Tenax - Menikini | + 09 | + 09 |
| 8 | Gabriele Bosisio | Tenax - Menikini | + 09 | + 09 |
| 9 | Linus Gerdemann | T-Mobile Team | + 09 | + 09 |
| 10 | Luca Solari | Team LPR | + 09 | + 09 |
| 11 | Ruggero Marzoli | Tinkoff Credit Systems | + 09 | + 09 |
| 12 | Alessandro Bertolini | Serramenti - Selle Italia | + 09 | + 09 |
| 13 | Gorazd Stangelj | Lampre-Fondital | + 09 | + 09 |
| 14 | Santo Anzà | Serramenti - Selle Italia | + 09 | + 09 |
| 15 | Donato Cannone | OTC Doors - Lauretana | + 09 | + 09 |
| 16 | Giampaolo Cheula | Barloworld | + 09 | + 09 |
| 17 | Micula Dematteis | Tenax - Menikini | + 09 | + 09 |
| 18 | Matteo Bono | Lampre-Fondital | + 09 | + 09 |
| 19 | David Canada | Saunier Duval - Prodir | + 09 | + 09 |
| 20 | Andrea Noè | Liquigas | + 09 | + 09 |
| 21 | Luca Mazzanti | Ceramica Panaria - Navigare | + 09 | + 09 |
| 22 | Bingen Fernández Bustinza | Cofidis | + 09 | + 09 |
| 23 | Andrei Kunitski | Acqua e Sapone | + 09 | + 09 |
| 24 | Jure Golcer | Tenax - Menikini | + 09 | + 09 |
| 25 | John-lee Augustyn | Barloworld | + 09 | + 09 |
| 26 | Riccardo Riccò | Saunier Duval - Prodir | + 09 | + 09 |
| 27 | Kanstantsin Sivtsov | Barloworld | + 09 | + 09 |
| 28 | Pedro Arreitunandia | Barloworld | + 09 | + 09 |
| 29 | Vincenzo Nibali | Liquigas | + 09 | + 09 |
| 30 | Volodymir Gustov | Team CSC | + 09 | + 09 |
| 31 | Vasil Kiryienka | Tinkoff Credit Systems | + 09 | + 09 |
| 32 | Mirko Celestino | Team Milram | + 13 | + 13 |
| 33 | Cristian Gasperoni | Ceramica Flaminia | + 15 | + 15 |
| 34 | Charles Wegelius | Liquigas | + 40 | + 40 |
| 35 | Enrico Gasparotto | Barloworld | + 44 | + 44 |
| 36 | Tiziano Dall'antonia | Ceramica Panaria - Navigare | + 44 | + 44 |
| 37 | René Mandri | AG2R Prévoyance | + 44 | + 44 |
| 38 | Daniele Contrini | Tinkoff Credit Systems | + 44 | + 44 |
| 39 | Simone Masciarelli | Acqua e Sapone | + 44 | + 44 |
| 40 | Paolo Bailetti | Team LPR | + 44 | + 44 |
| 41 | Julien Loubet | AG2R Prévoyance | + 44 | + 44 |
| 42 | Mickaël Buffaz | Cofidis | + 44 | + 44 |
| 43 | Cristiano Salerno | Tenax - Menikini | + 44 | + 44 |
| 44 | Andreas Dietziker | Team LPR | + 44 | + 44 |
| 45 | Roberto Traficante | Team LPR | + 44 | + 44 |
| 46 | Serhiy Honchar | T-Mobile Team | + 44 | + 44 |
| 47 | Salvatore Commesso | Tinkoff Credit Systems | + 44 | + 44 |
| 48 | Pavel Brutt | Tinkoff Credit Systems | + 44 | + 44 |
| 49 | Antonio Aldape Chavez | Ceramica Panaria - Navigare | + 44 | + 44 |
| 50 | Manuele Mori | Saunier Duval - Prodir | + 44 | + 44 |
| 51 | Gabriele Balducci | Acqua e Sapone | + 44 | + 44 |
| 52 | Stefano Boggia | Ceramica Flaminia | + 44 | + 44 |
| 53 | Mikhail Ignatiev | Tinkoff Credit Systems | + 44 | + 44 |
| 54 | Fabio Sacchi | Team Milram | + 44 | + 44 |
| 55 | Francesco Failli | Liquigas | + 48 | + 48 |
| 56 | Nicolas Hartmann | Cofidis | + 48 | + 48 |
| 57 | Alessandro Proni | Quick Step - Innergetic | + 48 | + 48 |
| 58 | Giovanni Visconti | Quick Step - Innergetic | + 50 | + 50 |
| 59 | Manuele Spadi | Ceramica Flaminia | + 50 | + 50 |
| 60 | Maurizio Varini | Ceramica Flaminia | + 54 | + 54 |
| 61 | Ivan Santaromita | Quick Step - Innergetic | + 01:01 | + 01:01 |
| 62 | Branislau Samoilau | Acqua e Sapone | + 01:15 | + 01:15 |
| 63 | Anders Lund | Team CSC | + 01:53 | + 01:53 |
| 64 | Volodymyr Zagorodniy | OTC Doors - Lauretana | + 02:16 | + 02:16 |
| 65 | Alberto Castaneda Jaime | Lampre-Fondital | + 02:18 | + 02:18 |
| 66 | Nikolai Trusov | Tinkoff Credit Systems | + 02:18 | + 02:18 |
| 67 | Vladimir Duma | Ceramica Flaminia | + 02:18 | + 02:18 |
| 68 | Marco Pinotti | T-Mobile Team | + 02:18 | + 02:18 |
| 69 | Paolo Bossoni | Lampre-Fondital | + 02:18 | + 02:18 |
| 70 | Gerald Ciolek | T-Mobile Team | + 02:18 | + 02:18 |
| 71 | Alessandro Bertuola | Tenax - Menikini | + 02:18 | + 02:18 |
| 72 | Guido Trentin | Saunier Duval - Prodir | + 02:18 | + 02:18 |
| 73 | Massimiliano Maisto | OTC Doors - Lauretana | + 02:18 | + 02:18 |
| 74 | Simone Bruson | OTC Doors - Lauretana | + 02:18 | + 02:18 |
| 75 | Tomasz Marczynski | Ceramica Flaminia | + 02:18 | + 02:18 |
| 76 | Piergiorgio Camussa | OTC Doors - Lauretana | + 02:18 | + 02:18 |
| 77 | Mattia Turrina | Serramenti - Selle Italia | + 02:18 | + 02:18 |
| 78 | Blaise Sonnery | AG2R Prévoyance | + 02:18 | + 02:18 |
| 79 | Giuseppe Guerini | T-Mobile Team | + 02:18 | + 02:18 |
| 80 | Allan Johansen | Team CSC | + 02:18 | + 02:18 |
| 81 | Carl Naibo | AG2R Prévoyance | + 02:18 | + 02:18 |
| 82 | Alessandro Donati | Acqua e Sapone | + 02:18 | + 02:18 |
| 83 | Aurélien Passeron | Acqua e Sapone | + 02:18 | + 02:18 |
| 84 | Rinaldo Nocentini | AG2R Prévoyance | + 02:18 | + 02:18 |
| 85 | Volodymyr Dyudya | Team Milram | + 02:18 | + 02:18 |
| 86 | Alexander Arekeev | Acqua e Sapone | + 02:18 | + 02:18 |
| 87 | Leonardo Bertagnolli | Liquigas | + 02:18 | + 02:18 |
| 88 | Alessandro Spezialetti | Liquigas | + 03:08 | + 03:08 |
| 89 | Paolo Bettini | Quick Step - Innergetic | + 03:31 | + 03:31 |
| 90 | Leonardo Scarselli | Quick Step - Innergetic | + 03:31 | + 03:31 |
| 91 | Christophe Moreau | AG2R Prévoyance | + 03:51 | + 03:51 |
| 92 | Enrico Poitschke | Team Milram | + 03:51 | + 03:51 |
| 93 | Marzio Bruseghin | Lampre-Fondital | + 04:11 | + 04:11 |
| 94 | Mauro Santambrogio | Tenax - Menikini | + 04:11 | + 04:11 |
| 95 | Alessandro Cortinovis | Team Milram | + 04:11 | + 04:11 |
| 96 | Paolo Fornaciari | Lampre-Fondital | + 04:11 | + 04:11 |
| 97 | Nazareno Rossi | Team LPR | + 04:11 | + 04:11 |
| 98 | Daniele Nardello | Team LPR | + 04:11 | + 04:11 |
| 99 | Raul Alarcon | Saunier Duval - Prodir | + 04:11 | + 04:11 |
| 100 | Antonio Bucciero | Ceramica Panaria - Navigare | + 04:11 | + 04:11 |
| 101 | Fortunato Baliani | Ceramica Panaria - Navigare | + 04:11 | + 04:11 |
| 102 | Roberto Petito | Liquigas | + 04:11 | + 04:11 |
| 103 | Luciano Pagliarini | Saunier Duval - Prodir | + 04:11 | + 04:11 |
| 104 | Marco Marcato | Team LPR | + 04:11 | + 04:11 |
| 105 | Damien Monier | Cofidis | + 04:11 | + 04:11 |
| 106 | Sergio Barbero | Serramenti - Selle Italia | + 04:11 | + 04:11 |
| 107 | Diego Caccia | Barloworld | + 04:11 | + 04:11 |
| 108 | Paolo Longo Borghini | Barloworld | + 04:11 | + 04:11 |
| 109 | Christian Murro | Tenax - Menikini | + 04:16 | + 04:16 |
| 110 | Yann Huguet | Cofidis | + 04:16 | + 04:16 |
| 111 | Rik Verbrugghe | Cofidis | + 04:16 | + 04:16 |
| 112 | Francesco Reda | OTC Doors - Lauretana | + 04:16 | + 04:16 |
| 113 | Crescenzo D'amore | OTC Doors - Lauretana | + 04:16 | + 04:16 |
| 114 | Asle Arvesen Kurt | Team CSC | + 05:20 | + 05:20 |
| 115 | Matteo Priamo | Ceramica Panaria - Navigare | + 05:20 | + 05:20 |
| 116 | Hubert Krys | Ceramica Flaminia | + 05:20 | + 05:20 |
| 117 | Eros Capecchi | Liquigas | + 06:31 | + 06:31 |
| 118 | Giosue Bonomi | Barloworld | + 06:31 | + 06:31 |
| 119 | Alexander Serov | Tinkoff Credit Systems | + 06:31 | + 06:31 |
| 120 | Claudio Cucinotta | Tenax - Menikini | + 06:34 | + 06:34 |
| 121 | Lars Michaelsen | Team CSC | + 06:34 | + 06:34 |
| 122 | Denis Bertolini | Serramenti - Selle Italia | + 06:34 | + 06:34 |
| 123 | Fabian Cancellara | Team CSC | + 06:34 | + 06:34 |
| 124 | Alberto Di Lorenzo | OTC Doors - Lauretana | + 06:34 | + 06:34 |
| 125 | Laurent Mangel | AG2R Prévoyance | + 06:34 | + 06:34 |
| 126 | Philippe Schnyder | Serramenti - Selle Italia | + 06:34 | + 06:34 |
| 127 | Ramiro Parra Iván | Cofidis | + 06:34 | + 06:34 |
| 128 | Elia Aggiano | Tinkoff Credit Systems | + 06:34 | + 06:34 |
| 129 | Lewis Perry James | Barloworld | + 06:34 | + 06:34 |
| 130 | Andrea Pagoto | Ceramica Panaria - Navigare | + 06:34 | + 06:34 |
| 131 | Walter Proch | Team LPR | + 06:34 | + 06:34 |
| 132 | Niki Terpstra | Team Milram | + 08:56 | + 08:56 |
| 133 | Roberto Ferrari | Tenax - Menikini | + 08:57 | + 08:57 |
| 134 | Andrea Rossi | Acqua e Sapone | + 08:57 | + 08:57 |
| 135 | Fabio Sabatini | Team Milram | + 08:57 | + 08:57 |
| 136 | Adam Wadecki | Ceramica Flaminia | + 08:57 | + 08:57 |
| 137 | Raivis Belohvosciks | Saunier Duval - Prodir | + 08:57 | + 08:57 |
| 138 | Ivan Degasperi | Serramenti - Selle Italia | + 08:57 | + 08:57 |
| 139 | Enrico Rossi | OTC Doors - Lauretana | + 10:07 | + 10:07 |
| 140 | Alessio Signego | OTC Doors - Lauretana | + 10:07 | + 10:07 |
| 141 | Mauro Facci | Quick Step - Innergetic | + 10:56 | + 10:56 |
| 142 | Daniele Callegarin | Team LPR | + 10:57 | + 10:57 |
| 143 | Enrico Degano | Barloworld | + 10:57 | + 10:57 |
| 144 | Davide Vigano | Quick Step - Innergetic | + 10:57 | + 10:57 |
| 145 | Martin Pedersen | Team CSC | + 10:57 | + 10:57 |
| 146 | Maurizio Bellin | Team LPR | + 11:07 | + 11:07 |