| # | Rider | Team | Time | Gap |
|---|---|---|---|---|
| 1 | Paolo Bettini | Quick Step - Innergetic | 04:18:31 | |
| 2 | Kim Kirchen | T-Mobile Team | + 52 | + 52 |
| 3 | Aleksandr Kuschynski | Ceramica Flaminia | + 52 | + 52 |
| 4 | Davide Rebellin | Gerolsteiner | + 52 | + 52 |
| 5 | Dmitriy Fofonov | Crédit Agricole | + 52 | + 52 |
| 6 | Andrea Tonti | Acqua e Sapone - Caffe Mokambo | + 52 | + 52 |
| 7 | Daniele Pietropolli | Team Tenax Salmilano | + 52 | + 52 |
| 8 | Sylvain Chavanel | Cofidis | + 52 | + 52 |
| 9 | Luca Mazzanti | Ceramica Panaria - Navigare | + 52 | + 52 |
| 10 | Andrea Moletta | Gerolsteiner | + 52 | + 52 |
| 11 | Massimo Giunti | Naturino - Sapore di Mare | + 52 | + 52 |
| 12 | Leonardo Bertagnolli | Cofidis | + 52 | + 52 |
| 13 | Maxime Monfort | Cofidis | + 52 | + 52 |
| 14 | Fränk Schleck | Team CSC | + 52 | + 52 |
| 15 | Christophe Le Mével | Crédit Agricole | + 52 | + 52 |
| 16 | Raffaele Illiano | Selle Italia - Serramenti | + 52 | + 52 |
| 17 | Anthony Charteau | Crédit Agricole | + 52 | + 52 |
| 18 | Vincenzo Nibali | Liquigas | + 52 | + 52 |
| 19 | Francesco Bellotti | Crédit Agricole | + 52 | + 52 |
| 20 | Gabriele Bosisio | Team Tenax Salmilano | + 52 | + 52 |
| 21 | Igor Astarloa | Barloworld | + 52 | + 52 |
| 22 | Pietro Caucchioli | Crédit Agricole | + 01:03 | + 01:03 |
| 23 | David Moncoutié | Cofidis | + 01:09 | + 01:09 |
| 24 | Przemyslaw Niemiec | Miche | + 02:54 | + 02:54 |
| 25 | Andreas Dietziker | Team LPR | + 02:54 | + 02:54 |
| 26 | Ivan Fanelli | Amore & Vita - McDonald's | + 03:11 | + 03:11 |
| 27 | Jérôme Pineau | Bouygues Telecom | + 03:11 | + 03:11 |
| 28 | Patrick Calcagni | Liquigas | + 03:11 | + 03:11 |
| 29 | Christophe Rinero | Saunier Duval - Prodir | + 03:11 | + 03:11 |
| 30 | Sergio Barbero | Selle Italia - Serramenti | + 03:11 | + 03:11 |