| # | Rider | Team | Time | Gap |
|---|---|---|---|---|
| 1 | Fernando Gaviria | Movistar Team | 04:35:27 | |
| 2 | Peter Sagan | TotalEnergies | + 00 | |
| 3 | Filippo Ganna | INEOS Grenadiers | + 00 | |
| 4 | Yves Lampaert | Soudal Quick-Step | + 00 | |
| 5 | Niklas Märkl | Team dsm-firmenich | + 00 | |
| 6 | Brandon Rivera | INEOS Grenadiers | + 00 | |
| 7 | Nicolas Tivani | Corratec Selle Italia | + 00 | |
| 8 | Quinn Simmons | Lidl-Trek | + 00 | |
| 9 | Laureano Rosas | Gremios por el Deporte Cutral Co. | + 00 | |
| 10 | Mathias Vacek | Lidl-Trek | + 00 | |
| 11 | Filippo Magli | Green Project-Bardiani CSF-Faizanè | + 00 | |
| 12 | Diego Sevilla | EOLO-Kometa Cycling Team | + 00 | |
| 13 | Tobias Lund Andresen | Team dsm-firmenich | + 00 | |
| 14 | Albert Torres | Movistar Team | + 00 | |
| 15 | Steff Cras | TotalEnergies | + 00 | |
| 16 | Yuriy Natarov | Astana Qazaqstan Team | + 00 | |
| 17 | Egan Bernal | INEOS Grenadiers | + 00 | |
| 18 | Matthew Riccitello | Israel-Premier Tech | + 00 | |
| 19 | Vinicius Rangel | Movistar Team | + 00 | |
| 20 | Marco Brenner | Team dsm-firmenich | + 00 | |
| 21 | Mattia Petrucci | Green Project-Bardiani CSF-Faizanè | + 00 | |
| 22 | Daniel Oss | TotalEnergies | + 00 | |
| 23 | Sergio Higuita | BORA-hansgrohe | + 00 | |
| 24 | Nicolas Paredes | SEP San Juan | + 00 | |
| 25 | Vicente Rojas | Chile | + 00 | |
| 26 | Daniel Martinez | INEOS Grenadiers | + 00 | |
| 27 | Einer Rubio | Movistar Team | + 00 | |
| 28 | Martin López | Astana Qazaqstan Team | + 00 | |
| 29 | Antwan Tolhoek | Lidl-Trek | + 00 | |
| 30 | Marco Frigo | Israel-Premier Tech | + 00 | |
| 31 | Javier Jamaica | Team Medellin-EPM | + 00 | |
| 32 | Brayan Sanchez | Team Medellin-EPM | + 00 | |
| 33 | Franco Buchanan | AV Fatima-San Juan Biker Motos-Electro 3 | + 00 | |
| 34 | Mateo Kalejmann | SEP San Juan | + 00 | |
| 35 | Alexander Konychev | Corratec Selle Italia | + 00 | |
| 36 | Manuele Tarozzi | Green Project-Bardiani CSF-Faizanè | + 00 | |
| 37 | Kevin Vermaerke | Team dsm-firmenich | + 00 | |
| 38 | Oscar Sevilla | Team Medellin-EPM | + 00 | |
| 39 | Abner González | Movistar Team | + 00 | |
| 40 | Alan Jousseaume | TotalEnergies | + 00 | |
| 41 | Remco Evenepoel | Soudal Quick-Step | + 00 | |
| 42 | Ángel López Miguel | Team Medellin-EPM | + 00 | |
| 43 | Jan Hirt | Soudal Quick-Step | + 00 | |
| 44 | Oier Lazkano | Movistar Team | + 00 | |
| 45 | Leandro Messineo | Chimbas te Quiero | + 00 | |
| 46 | Pablo Dotti Juan | SEP San Juan | + 00 | |
| 47 | Iversby Hvideberg Jonas | Team dsm-firmenich | + 56 | + 56 |
| 48 | Erik Fetter | EOLO-Kometa Cycling Team | + 00 | |
| 49 | Ryan Mullen | BORA-hansgrohe | + 00 | |
| 50 | Andrey Zeits | Astana Qazaqstan Team | + 00 | |
| 51 | Harold Tejada | Astana Qazaqstan Team | + 00 | |
| 52 | Leonardo Cobarrubia | SEP San Juan | + 04:21 | + 04:21 |
| 53 | Attilio Viviani | Corratec Selle Italia | + 11:50 | + 11:50 |
| 54 | Enrico Zanoncello | Green Project-Bardiani CSF-Faizanè | + 11:50 | + 11:50 |
| 55 | Jon Aberasturi | Lidl-Trek | + 11:50 | + 11:50 |
| 56 | Dario Cataldo | Lidl-Trek | + 11:50 | + 11:50 |
| 57 | Simone Raccani | EOLO-Kometa Cycling Team | + 11:50 | + 11:50 |
| 58 | Franklin Archibold | Panamá es Cultura y Valores | + 11:50 | + 11:50 |
| 59 | Jonas Koch | BORA-hansgrohe | + 11:50 | + 11:50 |
| 60 | Giacomo Nizzolo | Israel-Premier Tech | + 11:50 | + 11:50 |
| 61 | Danny van Poppel | BORA-hansgrohe | + 11:50 | + 11:50 |
| 62 | Elia Viviani | INEOS Grenadiers | + 11:50 | + 11:50 |
| 63 | Emiliano Ibarra | Gremios por el Deporte Cutral Co. | + 11:50 | + 11:50 |
| 64 | Jens Reynders | Israel-Premier Tech | + 11:50 | + 11:50 |
| 65 | Rick Zabel | Israel-Premier Tech | + 11:50 | + 11:50 |
| 66 | Cristhian Montoya | Team Banco Guayaquil | + 11:50 | + 11:50 |
| 67 | Davide Bais | EOLO-Kometa Cycling Team | + 11:50 | + 11:50 |
| 68 | Alexander Gil | AV Fatima-San Juan Biker Motos-Electro 3 | + 11:50 | + 11:50 |
| 69 | Iker Bonillo | Green Project-Bardiani CSF-Faizanè | + 11:50 | + 11:50 |
| 70 | Florian Lipowitz | BORA-hansgrohe | + 11:50 | + 11:50 |
| 71 | Cristofer Jurado | Panamá es Cultura y Valores | + 11:50 | + 11:50 |
| 72 | Hector Quintana | Chile | + 11:50 | + 11:50 |
| 73 | Maximiliano Richeze | Argentina | + 11:50 | + 11:50 |
| 74 | Stefano Gandin | Corratec Selle Italia | + 11:50 | + 11:50 |
| 75 | Delio Fernandez | AP Hotels & Resorts / Tavira / SC Farense | + 11:50 | + 11:50 |
| 76 | Ruben Simao | AP Hotels & Resorts / Tavira / SC Farense | + 11:50 | + 11:50 |
| 77 | Fabien Grellier | TotalEnergies | + 11:50 | + 11:50 |
| 78 | Alessandro Santaromita | Green Project-Bardiani CSF-Faizanè | + 11:50 | + 11:50 |
| 79 | Yevgeniy Gidich | Astana Qazaqstan Team | + 11:50 | + 11:50 |
| 80 | Manlio Moro | Italy | + 11:50 | + 11:50 |
| 81 | Venceslau Fernandes | AP Hotels & Resorts / Tavira / SC Farense | + 11:50 | + 11:50 |
| 82 | Steven Haro | Team Banco Guayaquil | + 11:50 | + 11:50 |
| 83 | Giovanni Lonardi | EOLO-Kometa Cycling Team | + 11:50 | + 11:50 |
| 84 | Simone Bevilacqua | EOLO-Kometa Cycling Team | + 11:50 | + 11:50 |
| 85 | Rafael Lourenço | AP Hotels & Resorts / Tavira / SC Farense | + 11:50 | + 11:50 |
| 86 | Ricardo Escuela | EC Municipalidad de Pocito | + 11:50 | + 11:50 |
| 87 | Fabio Duarte | Team Medellin-EPM | + 11:50 | + 11:50 |
| 88 | Victor Ocampo | Team Medellin-EPM | + 11:50 | + 11:50 |
| 89 | Sam Bennett | BORA-hansgrohe | + 11:50 | + 11:50 |
| 90 | Daniel Diaz Rodrigo | Municipalidad de Rawson | + 11:50 | + 11:50 |
| 91 | Maciej Bodnar | TotalEnergies | + 11:50 | + 11:50 |
| 92 | Pieter Serry | Soudal Quick-Step | + 11:50 | + 11:50 |
| 93 | Eric Fagundez | Uruguay | + 11:50 | + 11:50 |
| 94 | Fabio Jakobsen | Soudal Quick-Step | + 11:50 | + 11:50 |
| 95 | Gerardo Tivani | AV Fatima-San Juan Biker Motos-Electro 3 | + 11:50 | + 11:50 |
| 96 | Michael Mørkøv | Soudal Quick-Step | + 11:50 | + 11:50 |
| 97 | Sam Welsford | Team dsm-firmenich | + 19:57 | + 19:57 |
| 98 | Miguel Salgueiro | AP Hotels & Resorts / Tavira / SC Farense | + 19:57 | + 19:57 |
| 99 | Alex Strah | Panamá es Cultura y Valores | + 19:57 | + 19:57 |
| 100 | Javier Snihur Maximiliano | SEP San Juan | + 19:57 | + 19:57 |
| 101 | Alejandro Quilci | Gremios por el Deporte Cutral Co. | + 19:57 | + 19:57 |
| 102 | Nicolas Traico Maximiliano | Gremios por el Deporte Cutral Co. | + 19:57 | + 19:57 |
| 103 | Carlos Gutiérrez | Team Banco Guayaquil | + 19:57 | + 19:57 |
| 104 | Nixon Rosero | Team Banco Guayaquil | + 19:57 | + 19:57 |
| 105 | Maximiliano Navarrete | Gremios por el Deporte Cutral Co. | + 22:50 | + 22:50 |
| 106 | Liam Bertazzo | Italy | + 22:50 | + 22:50 |
| 107 | Martin Reyes Jose | EC Municipalidad de Pocito | + 22:50 | + 22:50 |
| 108 | Yelko Gomez | Panamá es Cultura y Valores | + 22:50 | + 22:50 |
| 109 | Ricardo Dominguez Mauricio | AV Fatima-San Juan Biker Motos-Electro 3 | + 22:50 | + 22:50 |
| 110 | Gleb Syritsa | Astana Qazaqstan Team | + 22:50 | + 22:50 |
| 111 | Cristian Pita | Team Banco Guayaquil | + 22:50 | + 22:50 |
| 112 | Alejandro Duran | Chimbas te Quiero | + 22:50 | + 22:50 |
| 113 | Luis Rodriguez Jose | Chile | + 22:50 | + 22:50 |
| 114 | Mauro Richeze | Chimbas te Quiero | + 22:50 | + 22:50 |
| 115 | Nicolas Cabrera | Chile | + 22:50 | + 22:50 |
| 116 | Wladimir Martinez | AV Fatima-San Juan Biker Motos-Electro 3 | + 22:50 | + 22:50 |
| 117 | Agustin Videla | Municipalidad de Rawson | + 22:50 | + 22:50 |
| 118 | Hugo Ruiz | SEP San Juan | + 22:50 | + 22:50 |
| 119 | Sergio Aguirre | Municipalidad de Rawson | + 22:50 | + 22:50 |
| 120 | Manuel Lira Eguiguren | Chile | + 22:50 | + 22:50 |
| 121 | Michele Scartezzini | Italy | + 22:50 | + 22:50 |
| 122 | German Lopez Franco | Argentina | + 22:50 | + 22:50 |
| 123 | Francesco Lamon | Italy | + 22:50 | + 22:50 |
| 124 | Davide Boscaro | Italy | + 22:50 | + 22:50 |
| 125 | Mattia Pinazzi | Italy | + 22:50 | + 22:50 |
| 126 | Roderyck Asconeguy | Uruguay | + 22:50 | + 22:50 |
| 127 | Nahuel Mendez Marcelo | Municipalidad de Rawson | + 22:50 | + 22:50 |
| 128 | Bredio Ruiz | Panamá es Cultura y Valores | + 30:13 | + 30:13 |
| 129 | Emiliano Contreras | Chimbas te Quiero | + 30:13 | + 30:13 |
| 130 | Bolivar Espinosa | Panamá es Cultura y Valores | + 30:13 | + 30:13 |
| 131 | Javier Melivillo Juan | EC Municipalidad de Pocito | + 30:13 | + 30:13 |
| 132 | Juan Caorsi | Uruguay | + 30:13 | + 30:13 |
| 133 | Mauricio Paez | Gremios por el Deporte Cutral Co. | + 32:26 | + 32:26 |
| 134 | Marcos Mendez | Argentina | + 32:26 | + 32:26 |
| 135 | Lukas Dundic | Argentina | + 32:26 | + 32:26 |
| 136 | Javier Lopez Federico | EC Municipalidad de Pocito | + 32:26 | + 32:26 |
| 137 | Francisco Kotsakis Lagos | Chile | + 32:26 | + 32:26 |
| 138 | Pedro Gordillo | Municipalidad de Rawson | + 32:26 | + 32:26 |