| # | Rider | Team | Time | Gap |
|---|---|---|---|---|
| 1 | Philippe Gilbert | Omega Pharma-Lotto | 06:46:32 | |
| 2 | Michele Scarponi | Androni Giocattoli | + 12 | + 12 |
| 3 | Pablo Lastras | Caisse d'Epargne | + 55 | + 55 |
| 4 | Jakob Fuglsang | Team Saxo Bank | + 01:08 | + 01:08 |
| 5 | Vincenzo Nibali | Liquigas-Doimo | + 01:08 | + 01:08 |
| 6 | Samuel Sánchez | Euskaltel-Euskadi | + 01:12 | + 01:12 |
| 7 | Mikel Nieve | Euskaltel-Euskadi | + 02:07 | + 02:07 |
| 8 | Mauro Santambrogio | BMC Racing Team | + 03:01 | + 03:01 |
| 9 | Carlos Barredo | Quick Step | + 03:25 | + 03:25 |
| 10 | Giampaolo Caruso | Ceramica Flaminia | + 03:50 | + 03:50 |
| 11 | Vladimir Gusev | Team Katusha | + 04:24 | + 04:24 |
| 12 | Rigoberto Uran | Caisse d'Epargne | + 05:13 | + 05:13 |
| 13 | Bauke Mollema | Rabobank | + 05:13 | + 05:13 |
| 14 | Dries Devenyns | Quick Step | + 05:32 | + 05:32 |
| 15 | Fabian Wegmann | Team Milram | + 05:52 | + 05:52 |
| 16 | Greg van Avermaet | Omega Pharma-Lotto | + 06:00 | + 06:00 |
| 17 | Vladimir Miholjevic | Acqua e Sapone | + 06:10 | + 06:10 |
| 18 | Luca Mazzanti | Team Katusha | + 06:10 | + 06:10 |
| 19 | Maciej Paterski | Liquigas-Doimo | + 06:10 | + 06:10 |
| 20 | Maxime Monfort | Team HTC - Columbia | + 06:10 | + 06:10 |
| 21 | Chris Horner | RadioShack | + 06:10 | + 06:10 |
| 22 | Guillaume Bonnafond | AG2R La Mondiale | + 06:41 | + 06:41 |
| 23 | Jurgen van Goolen | Omega Pharma-Lotto | + 08:23 | + 08:23 |
| 24 | Serge Pauwels | Sky Professional Cycling Team | + 09:38 | + 09:38 |
| 25 | Luis Rubiera José | RadioShack | + 09:52 | + 09:52 |
| 26 | Ludovic Turpin | AG2R La Mondiale | + 11:50 | + 11:50 |
| 27 | Manuele Mori | Lampre-Farnese Vini | + 12:30 | + 12:30 |
| 28 | José Serpa | Androni Giocattoli | + 12:42 | + 12:42 |
| 29 | Samuel Dumoulin | Cofidis | + 12:44 | + 12:44 |
| 30 | Assan Bazayev | Astana | + 12:46 | + 12:46 |
| 31 | Thomas Peterson | Garmin-Transitions | + 12:46 | + 12:46 |
| 32 | Johannes Fröhlinger | Team Milram | + 14:34 | + 14:34 |
| 33 | Petter Nordhaug Lars | Sky Professional Cycling Team | + 20:39 | + 20:39 |
| 34 | Aleksejs Saramotins | Team HTC - Columbia | + 21:35 | + 21:35 |