| # | Rider | Team | Time | Gap |
|---|---|---|---|---|
| 1 | Tadej Pogacar | UAE Team Emirates | 06:21:22 | |
| 2 | Enric Mas | Movistar Team | + 00 | |
| 3 | Mikel Landa | Bahrain Victorious | + 10 | + 10 |
| 4 | Sergio Higuita | BORA-hansgrohe | + 52 | + 52 |
| 5 | Carlos Rodriguez | INEOS Grenadiers | + 52 | + 52 |
| 6 | Alejandro Valverde | Movistar Team | + 01:24 | + 01:24 |
| 7 | Bauke Mollema | Trek-Segafredo | + 01:24 | + 01:24 |
| 8 | Rudy Molard | Groupama-FDJ | + 01:24 | + 01:24 |
| 9 | Romain Bardet | Team DSM | + 01:24 | + 01:24 |
| 10 | Adam Yates | INEOS Grenadiers | + 01:26 | + 01:26 |
| 11 | Andrea Piccolo | EF Education-EasyPost | + 01:58 | + 01:58 |
| 12 | Warren Barguil | Team Arkéa-Samsic | + 01:58 | + 01:58 |
| 13 | Ilan van Wilder | Quick-Step Alpha Vinyl Team | + 01:58 | + 01:58 |
| 14 | Clément Berthet | AG2R Citroën Team | + 01:58 | + 01:58 |
| 15 | Giulio Ciccone | Trek-Segafredo | + 02:01 | + 02:01 |
| 16 | Jonas Vingegaard | Jumbo-Visma | + 02:03 | + 02:03 |
| 17 | Daniel Martinez | INEOS Grenadiers | + 02:14 | + 02:14 |
| 18 | Aleksandr Vlasov | BORA-hansgrohe | + 02:14 | + 02:14 |
| 19 | Mikkel Honore | Quick-Step Alpha Vinyl Team | + 02:14 | + 02:14 |
| 20 | Mauri Vansevenant | Quick-Step Alpha Vinyl Team | + 02:14 | + 02:14 |
| 21 | Rigoberto Uran | EF Education-EasyPost | + 02:14 | + 02:14 |
| 22 | Matteo Fabbro | BORA-hansgrohe | + 02:14 | + 02:14 |
| 23 | Rafal Majka | UAE Team Emirates | + 02:17 | + 02:17 |
| 24 | Vincenzo Nibali | Astana Qazaqstan Team | + 02:17 | + 02:17 |
| 25 | Rémy Rochas | Cofidis | + 02:41 | + 02:41 |
| 26 | Diego Ulissi | UAE Team Emirates | + 02:41 | + 02:41 |
| 27 | Michael Storer | Groupama-FDJ | + 02:41 | + 02:41 |
| 28 | Davide Formolo | UAE Team Emirates | + 03:09 | + 03:09 |
| 29 | Alexis Vuillermoz | TotalEnergies | + 03:25 | + 03:25 |
| 30 | Quentin Pacher | Groupama-FDJ | + 03:25 | + 03:25 |
| 31 | Pierre Latour | TotalEnergies | + 03:25 | + 03:25 |
| 32 | Guillaume Martin | Cofidis | + 03:25 | + 03:25 |
| 33 | Jan Bakelants | Intermarché-Wanty-Gobert Matériaux | + 03:25 | + 03:25 |
| 34 | Neilson Powless | EF Education-EasyPost | + 04:21 | + 04:21 |
| 35 | Simone Petilli | Intermarché-Wanty-Gobert Matériaux | + 04:22 | + 04:22 |
| 36 | Mark Padun | EF Education-EasyPost | + 04:51 | + 04:51 |
| 37 | Stefano Oldani | Alpecin-Deceuninck | + 05:04 | + 05:04 |
| 38 | Marco Brenner | Team DSM | + 06:11 | + 06:11 |
| 39 | Hermann Pernsteiner | Bahrain Victorious | + 06:11 | + 06:11 |
| 40 | Andreas Leknessund | Team DSM | + 06:50 | + 06:50 |
| 41 | Andreas Kron | Lotto-Soudal | + 06:53 | + 06:53 |
| 42 | Nick Schultz | Team BikeExchange-Jayco | + 06:53 | + 06:53 |
| 43 | Xandro Meurisse | Alpecin-Deceuninck | + 06:53 | + 06:53 |
| 44 | Alan Jousseaume | TotalEnergies | + 06:53 | + 06:53 |
| 45 | Edoardo Zambanini | Bahrain Victorious | + 06:53 | + 06:53 |
| 46 | Simon Geschke | Cofidis | + 06:53 | + 06:53 |
| 47 | Sam Oomen | Jumbo-Visma | + 06:57 | + 06:57 |
| 48 | Jesus Herrada | Cofidis | + 07:01 | + 07:01 |
| 49 | Louis Barré | Team Arkéa-Samsic | + 07:27 | + 07:27 |
| 50 | Antwan Tolhoek | Trek-Segafredo | + 07:40 | + 07:40 |
| 51 | Julian Alaphilippe | Quick-Step Alpha Vinyl Team | + 07:40 | + 07:40 |
| 52 | Simon Guglielmi | Team Arkéa-Samsic | + 08:00 | + 08:00 |
| 53 | Alessandro de Marchi | Israel-Premier Tech | + 08:00 | + 08:00 |
| 54 | Lawson Craddock | Team BikeExchange-Jayco | + 08:31 | + 08:31 |
| 55 | Alessandro Fancellu | EOLO-Kometa Cycling Team | + 08:52 | + 08:52 |
| 56 | Mathieu Burgaudeau | TotalEnergies | + 09:51 | + 09:51 |
| 57 | Chris Hamilton | Team DSM | + 10:13 | + 10:13 |
| 58 | Tim Wellens | Lotto-Soudal | + 10:26 | + 10:26 |
| 59 | Simone Velasco | Astana Qazaqstan Team | + 10:26 | + 10:26 |
| 60 | Wilco Kelderman | BORA-hansgrohe | + 10:26 | + 10:26 |
| 61 | Matej Mohoric | Bahrain Victorious | + 10:26 | + 10:26 |
| 62 | Damiano Caruso | Bahrain Victorious | + 10:26 | + 10:26 |
| 63 | Giovanni Aleotti | BORA-hansgrohe | + 10:26 | + 10:26 |
| 64 | Jay Vine | Alpecin-Deceuninck | + 10:26 | + 10:26 |
| 65 | Ángel López Miguel | Astana Qazaqstan Team | + 11:09 | + 11:09 |
| 66 | Kévin Vauquelin | Team Arkéa-Samsic | + 11:26 | + 11:26 |
| 67 | Patrick Konrad | BORA-hansgrohe | + 11:26 | + 11:26 |
| 68 | Tao Geoghegan Hart | INEOS Grenadiers | + 11:26 | + 11:26 |
| 69 | Joaquin Rojas José | Movistar Team | + 11:26 | + 11:26 |
| 70 | Laurens Huys | Intermarché-Wanty-Gobert Matériaux | + 11:29 | + 11:29 |
| 71 | Jakob Fuglsang | Israel-Premier Tech | + 13:37 | + 13:37 |
| 72 | Mark Donovan | Team DSM | + 13:37 | + 13:37 |
| 73 | Clément Champoussin | AG2R Citroën Team | + 13:37 | + 13:37 |
| 74 | Aurélien Paret-peintre | AG2R Citroën Team | + 13:37 | + 13:37 |
| 75 | Filippo Zana | Bardiani CSF Faizanè | + 13:37 | + 13:37 |
| 76 | Thymen Arensman | Team DSM | + 13:37 | + 13:37 |
| 77 | Robert Gesink | Jumbo-Visma | + 14:56 | + 14:56 |
| 78 | Chris Harper | Jumbo-Visma | + 14:56 | + 14:56 |
| 79 | Koen Bouwman | Jumbo-Visma | + 14:56 | + 14:56 |
| 80 | Victor de La Parte | TotalEnergies | + 14:56 | + 14:56 |
| 81 | Marc Hirschi | UAE Team Emirates | + 15:41 | + 15:41 |
| 82 | Alexandre Balmer | Team BikeExchange-Jayco | + 16:52 | + 16:52 |
| 83 | Luca Covili | Bardiani CSF Faizanè | + 16:52 | + 16:52 |
| 84 | Tobias Bayer | Alpecin-Deceuninck | + 18:23 | + 18:23 |
| 85 | Eduard Prades | Caja Rural-Seguros RGA | + 18:23 | + 18:23 |
| 86 | Mattia Bais | Drone Hopper-Androni Giocattoli | + 18:23 | + 18:23 |
| 87 | Corbin Strong | Israel-Premier Tech | + 18:23 | + 18:23 |
| 88 | Santiago Umba | Drone Hopper-Androni Giocattoli | + 18:23 | + 18:23 |
| 89 | Reto Hollenstein | Israel-Premier Tech | + 18:23 | + 18:23 |
| 90 | Kristian Sbaragli | Alpecin-Deceuninck | + 18:23 | + 18:23 |
| 91 | Simone Ravanelli | Drone Hopper-Androni Giocattoli | + 18:23 | + 18:23 |
| 92 | Aritz Bagües | Caja Rural-Seguros RGA | + 18:23 | + 18:23 |
| 93 | Alessandro Tonelli | Bardiani CSF Faizanè | + 18:23 | + 18:23 |
| 94 | Imanol Erviti | Movistar Team | + 18:23 | + 18:23 |
| 95 | Jorge Arcas | Movistar Team | + 18:23 | + 18:23 |
| 96 | Davide Gabburo | Bardiani CSF Faizanè | + 19:20 | + 19:20 |
| 97 | Fredrik Hagen Carl | Israel-Premier Tech | + 19:27 | + 19:27 |
| 98 | Omar El Gouzi | Bardiani CSF Faizanè | + 23:53 | + 23:53 |
| 99 | Mirco Maestri | EOLO-Kometa Cycling Team | + 26:28 | + 26:28 |
| 100 | Davide Bais | EOLO-Kometa Cycling Team | + 26:28 | + 26:28 |
| 101 | Julien Bernard | Trek-Segafredo | + 26:28 | + 26:28 |
| 102 | Felix Großschartner | BORA-hansgrohe | + 26:28 | + 26:28 |
| 103 | Samuele Rivi | EOLO-Kometa Cycling Team | + 26:28 | + 26:28 |
| 104 | Erik Fetter | EOLO-Kometa Cycling Team | + 26:28 | + 26:28 |
| 105 | Kamil Malecki | Lotto-Soudal | + 27:22 | + 27:22 |
| 106 | Johan Jacobs | Movistar Team | + 28:21 | + 28:21 |
| 107 | Paul Lapeira | AG2R Citroën Team | + 30:34 | + 30:34 |