| # | Rider | Team | Time | Gap |
|---|---|---|---|---|
| 1 | Tadej Pogacar | UAE Team Emirates | 05:14:43 | |
| 2 | Tom Pidcock | INEOS Grenadiers | + 01:54 | + 01:54 |
| 3 | Davide Piganzoli | Team Polti Kometa | + 01:54 | + 01:54 |
| 4 | Michael Woods | Israel-Premier Tech | + 01:54 | + 01:54 |
| 5 | Simon Yates | Team Jayco-AlUla | + 02:02 | + 02:02 |
| 6 | Roger Adrià | Red Bull-BORA-hansgrohe | + 02:04 | + 02:04 |
| 7 | Wilco Kelderman | Team Visma | Lease a Bike | + 02:04 | + 02:04 |
| 8 | Enric Mas | Movistar Team | + 02:08 | + 02:08 |
| 9 | Archie Ryan | EF Education-EasyPost | + 02:13 | + 02:13 |
| 10 | Lorenzo Fortunato | Astana Qazaqstan Team | + 02:15 | + 02:15 |
| 11 | Cristian Scaroni | Astana Qazaqstan Team | + 02:18 | + 02:18 |
| 12 | Adam Yates | UAE Team Emirates | + 02:20 | + 02:20 |
| 13 | Simone Velasco | Astana Qazaqstan Team | + 02:25 | + 02:25 |
| 14 | Attila Valter | Team Visma | Lease a Bike | + 02:28 | + 02:28 |
| 15 | Nairo Quintana | Movistar Team | + 02:28 | + 02:28 |
| 16 | Guillaume Martin | Cofidis | + 02:29 | + 02:29 |
| 17 | Matteo Jorgenson | Team Visma | Lease a Bike | + 02:29 | + 02:29 |
| 18 | Domenico Pozzovivo | VF Group-Bardiani CSF-Faizanè | + 02:29 | + 02:29 |
| 19 | Dylan Teuns | Israel-Premier Tech | + 02:36 | + 02:36 |
| 20 | Florian Lipowitz | Red Bull-BORA-hansgrohe | + 02:37 | + 02:37 |
| 21 | Rémy Rochas | Groupama-FDJ | + 02:55 | + 02:55 |
| 22 | Giulio Pellizzari | VF Group-Bardiani CSF-Faizanè | + 03:00 | + 03:00 |
| 23 | Marco Brenner | Tudor Pro Cycling Team | + 03:30 | + 03:30 |
| 24 | Gianmarco Garofoli | Astana Qazaqstan Team | + 03:43 | + 03:43 |
| 25 | Ben Healy | EF Education-EasyPost | + 03:45 | + 03:45 |
| 26 | Walter Calzoni | Q36.5 Pro Cycling Team | + 03:59 | + 03:59 |
| 27 | Jai Hindley | Red Bull-BORA-hansgrohe | + 04:17 | + 04:17 |
| 28 | Johannes Staune-mittet | Team Visma | Lease a Bike | + 04:17 | + 04:17 |
| 29 | Aurélien Paret-peintre | Decathlon AG2R La Mondiale Team | + 04:17 | + 04:17 |
| 30 | Iker Mintegi | Euskaltel-Euskadi | + 04:24 | + 04:24 |
| 31 | Filippo Zana | Team Jayco-AlUla | + 07:15 | + 07:15 |
| 32 | Txomin Juaristi | Euskaltel-Euskadi | + 07:19 | + 07:19 |
| 33 | Edgar Cadena | Petrolike | + 07:21 | + 07:21 |
| 34 | Georg Steinhauser | EF Education-EasyPost | + 07:29 | + 07:29 |
| 35 | Thymen Arensman | INEOS Grenadiers | + 07:36 | + 07:36 |
| 36 | Nicolas Prodhomme | Decathlon AG2R La Mondiale Team | + 07:37 | + 07:37 |
| 37 | Fredrik Hagen Carl | Q36.5 Pro Cycling Team | + 07:49 | + 07:49 |
| 38 | Ruben Fernandez | Cofidis | + 07:50 | + 07:50 |
| 39 | Lawrence Warbasse | Decathlon AG2R La Mondiale Team | + 07:50 | + 07:50 |
| 40 | Damiano Caruso | Bahrain Victorious | + 07:50 | + 07:50 |
| 41 | Giovanni Aleotti | Red Bull-BORA-hansgrohe | + 07:50 | + 07:50 |
| 42 | Ion Izagirre | Cofidis | + 07:50 | + 07:50 |
| 43 | Giulio Ciccone | Lidl-Trek | + 07:55 | + 07:55 |
| 44 | Wout Poels | Bahrain Victorious | + 08:25 | + 08:25 |
| 45 | Davide de Cassan | Team Polti Kometa | + 08:25 | + 08:25 |
| 46 | Edward Dunbar | Team Jayco-AlUla | + 08:48 | + 08:48 |
| 47 | Alex Baudin | Decathlon AG2R La Mondiale Team | + 09:32 | + 09:32 |
| 48 | Luca Covili | VF Group-Bardiani CSF-Faizanè | + 10:42 | + 10:42 |
| 49 | Sam Oomen | Lidl-Trek | + 11:04 | + 11:04 |
| 50 | George Bennett | Israel-Premier Tech | + 11:26 | + 11:26 |
| 51 | Harrison Wood | Cofidis | + 11:42 | + 11:42 |
| 52 | Tijmen Graat | Team Visma | Lease a Bike | + 12:07 | + 12:07 |
| 53 | Mauricio Zapata | Petrolike | + 12:37 | + 12:37 |